艾什是一部剧情/犯罪/惊悚片，影片讲述了一名杀手Asher（朗·普尔曼 饰）在执行最后一个任务时，遇到了一个让他生活颠覆的女人（法米克·詹森 饰）。
Asher (Ron Perlman) is a contract killer who's spent the better part of his life ending other lives, taking orders from Avi (Richard Dreyfuss). He lives a lonely existence, making friends out of fine wine and good food, resenting his apprentice, Uzi (Peter Facinelli), who's taking jobs from him due to youth. When Avi hands Asher three contracts for a revenge scheme, the hitman takes the job, only to lose consciousness due to health issues, making accidental contact with Sophie (Famke Janssen), a ballet teacher distraught over mother Dora (Jacqueline Bisset), who's losing her battle with dementia. Asher and Sophie make a connection, embarking on a tentative courtship where the murderer can't share anything about his life. As the pair work out their flirtations, Asher is forced to pair with Uzi on a group hit, and when that goes bad for a moment, the veteran soon becomes marked for death, threatening all the good that's come into his world.